Can I make it to Los Angeles in 6 hours of driving?

That interstate is very busy most of the time, but on Fridays and weekends is even worse. Maybe it wont be too bad early in the morning but if you are planning on attending a baseball game keep in mind that once you started to get close to the stadium the traffic its going to be crazy slow, getting parking would take some time too, now add to that some more time to actually getting in the stadium, if you don't have tickets, then you can add about an hour just to buy them, so if you can leave a little bit earlier it would be best thing for you. Take your time and enjoy the game.